Blog Comments

Kinetica Online is pleased to provide direct links to commentaries from our senior editor Dr. Steven Pelech has posted on other blogs sites. Most of these comments appear on the GenomeWeb Daily Scan website, which in turn highlight interesting blogs that have been posted at numerous sites in the blogosphere since the beginning of 2010. A wide variety of topical subjects are covered ranging from the latest scientific breakthroughs, research trends, politics and career advice. The original blogs and Dr. Pelech’s comments are summarized here under the title of the original blog. Should viewers wish to add to these discussions, they should add their comments at the original blog sites.

The views expressed by Dr. Pelech do not necessarily reflect those of the other management and staff at Kinexus Bioinformatics Corporation. However, we wish to encourage healthy debate that might spur improvements in how biomedical research is supported and conducted.

Swap sweep theory

Evolution of a Fruit Fly, Evolution of a Human

Researchers at UC Irvine have published research results with fruit flies that confirm the so-called "soft sweep" theory of evolutionary that the exploitation of small differences in many different genes were responsible for the emergence of new traits, rather that a large mutation in single genes. "If complex traits, including susceptibility to disease, are influenced by tens or hundreds of genes, then treatments targeted to single genes won't be very effective". S. Pelech questions the applicability of studies with flies that can bred after 8.5 days with humans that must be about 12 years old before they are capable of reproduction, but notes that it is already well appreciated that many genes influence complex traits, and susceptibility to diseases does not arise from just a few genes. Read More...